Raw materials that survive regulatory review.
GMP-grade magnetic beads, monoclonal antibodies, recombinant proteins and serum-free media for cell and gene therapy — supplied with the DMF references, COAs and audit package your CMC team will be asked for.
Five steps. One supplier for each of them.
Most process failures trace back to a reagent change halfway through development. Build the whole chain from one qualified source and the tech transfer gets shorter.
Four platforms, one quality system.
Beads, antibodies, proteins and media are developed in-house, so a change in one does not invalidate the others.
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0304AI designs the experiment. The bench proves it.
Send a target sequence and a constraint — yield, solubility, timeline. Models propose the construct, the host and the induction conditions; our lab runs the matrix and returns the data. What fails becomes the input for the next round.
Codon-optimised, host-matched construct — not a catalogue default
Solubility and yield ranked before anything is synthesised
24–96 condition matrix in one bench run, titre and soluble fraction
Every result, including failures, updates the next design
Built for the cell type you are manufacturing.
Each application page maps the workflow step to the reagent, with the grade and documentation you need at that stage.
Engineered T cells, from apheresis to fill-finish
A matched isolation–activation–expansion set built around CD3/CD28 signalling, so your process development team can lock a single vendor for the critical reagents.
The paperwork is the product.
Any supplier can ship a vial. What decides whether your IND moves is whether the reagent has a filing, a batch record and an audit trail behind it.
When the catalogue does not fit, we build the reagent.
Bead conjugation, GMP protein expression, gene editing and formulation — developed against your process, not a generic spec.
Magnetic Bead Customisation
Conjugate your antibody or ligand to 50 nm – 4.5 µm magnetic particles, with coupling density, blocking and release chemistry developed against your target cell.
GMP Protein Expression & Purification
Constructs designed by the model, expressed in E. coli, HEK293 or CHO, then scaled through process development into GMP manufacturing.
Gene Editing Services
CRISPR and knock-in/knock-out engineering for cell lines and primary cells, with off-target assessment and clonal characterisation.
Technical notes from the people who make it.
Application notes, protocols and regulatory explainers — written by our R&D and quality teams.
RegulatoryWhat an FDA DMF actually buys you when you licence a CGT raw material
A Type II DMF is not an approval — it is a closed reference. Here is how sponsors use DMF 038124 during an IND review, and what the auditor will ask for next.
Read
TechnicalBead size, steric hindrance and why 50 nm changes your activation readout
Comparing 4.5 µm and 50 nm particles in CD3/CD28 activation: the effect on cell-surface availability, expansion fold and downstream transduction efficiency.
Read
ProtocolFeeder-free NK expansion from cryopreserved CBMC: a 14-day protocol
A step-by-step protocol using AMMS® NK Cell Culture Kit 3.0, including seeding density, feeding cadence and the purity you should expect at day 14.
ReadSend us your spec. We will send back a protocol.
Tell us the cell type, scale and grade you are working at. A technical specialist replies within one business day — with the datasheet, the DMF letter of authorisation if relevant, and a quote.
